LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
ciRS-7 miR-7 AKT AKT1;AKT;CWS6;PKB;PKB-ALPHA;PRKBA;RAC;RAC-ALPHA details
Cholinergic synapse;HIF-1 signaling pathway;Chemokine signaling pathway;MAPK signaling pathway;Small cell lung cancer;Toll-like receptor signaling pathway;Fc epsilon RI signaling pathway;T cell receptor signaling pathway;ErbB signaling pathway;Carbohydrate digestion and absorption;Chagas disease (American trypanosomiasis);mTOR signaling pathway;PI3K-Akt signaling pathway;Hepatitis B;HTLV-I infection;Pathways in cancer;Toxoplasmosis;Colorectal cancer;Endometrial cancer;Jak-STAT signaling pathway;Neurotrophin signaling pathway;Influenza A;Proteoglycans in cancer; Measles;Dopaminergic synapse;Tuberculosis;Prostate cancer;Non-small cell lung cancer;Apoptosis;Progesterone-mediated oocyte maturation;Melanoma;Chronic myeloid leukemia; B cell receptor signaling pathway; Insulin signaling pathway;Renal cell carcinoma;Estrogen signaling pathway;VEGF signaling pathway;Osteoclast differentiation;Glioma;Epstein-Barr virus infection; Focal adhesion;Tight junction;Hepatitis C;Fc gamma R-mediated phagocytosis;Pancreatic cancer;Acute myeloid leukemia;Adipocytokine signaling pathway
details
Furthermore, overexpression of ciRS-7 blocked the miR-7-induced tumor suppression in MGC-803 and HGC-27 cells and led to a more aggressive oncogenic phenotype, via antagonizing miR-7-mediated PTEN/PI3K/AKT pathway.
details
Overexpression of Circular RNA ciRS-7 Abrogates the Tumor Suppressive Effect of miR-7 on Gastric Cancer via PTEN/PI3K/AKT Signaling Pathway.
Gastric cancer J Cell Biochem 28608528
CCAT1 miR-7 HOXB13 HOXB13;PSGD details
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In cytoplasm, CCAT1 regulates HOXB13 as a molecular decoy for miR-7, a microRNA that targets both CCAT1 and HOXB13, thus facilitating cell growth and migration.
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H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma
Esophageal Squamous Cell Carcinoma Nucleic Acids Res 27956498
ciRS-7 miR-7 PI3K details
details
Furthermore, overexpression of ciRS-7 blocked the miR-7-induced tumor suppression in MGC-803 and HGC-27 cells and led to a more aggressive oncogenic phenotype, via antagonizing miR-7-mediated PTEN/PI3K/AKT pathway.
details
Overexpression of Circular RNA ciRS-7 Abrogates the Tumor Suppressive Effect of miR-7 on Gastric Cancer via PTEN/PI3K/AKT Signaling Pathway.
Gastric cancer J Cell Biochem 28608528
ciRS-7 miR-7 PTEN PTEN;10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1 details
p53 signaling pathway;Inositol phosphate metabolism;Prostate cancer;Phosphatidylinositol signaling system;mTOR signaling pathway;PI3K-Akt signaling pathway;Focal adhesion;Tight junction;Hepatitis B;Pathways in cancer;Melanoma;Endometrial cancer;Glioma;Small cell lung cancer
details
Furthermore, overexpression of ciRS-7 blocked the miR-7-induced tumor suppression in MGC-803 and HGC-27 cells and led to a more aggressive oncogenic phenotype, via antagonizing miR-7-mediated PTEN/PI3K/AKT pathway.
details
Overexpression of Circular RNA ciRS-7 Abrogates the Tumor Suppressive Effect of miR-7 on Gastric Cancer via PTEN/PI3K/AKT Signaling Pathway.
Gastric cancer J Cell Biochem 28608528
CCAT1 miR-7 SPRY4 SPRY4;HH17 details
Jak-STAT signaling pathway
details
Mechanistic investigations found that CCAT1 could serve as a scaffold for two distinct epigenetic modification complexes (5? domain of CCAT1 binding Polycomb Repressive Complex 2 (PRC2) while 3? domain of CCAT1 binding SUV39H1) and modulate the histone methylation of promoter of SPRY4 (sprouty RTK signaling antagonist 4) in nucleus
details
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma
Esophageal Squamous Cell Carcinoma Nucleic Acids Res 27956498