| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| FTH1P3 | miR-224-5p | fizzled 5 | FZD5；C2orf31；HFZ5 | details
Wnt signaling pathway；Hippo signaling pathway；Melanogenesis；HTLV-I infection；Pathways in cancer；Proteoglycans in cancer；Basal cell carcinoma
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Moreover, FTH1P3 acted as a competitive endogenous RNA (ceRNA), effectively becoming sponge for miR-224-5p and thereby modulating the expression of fizzled 5.
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Long non-coding RNA FTH1P3 facilitates oral squamous cell carcinoma progression by acting as a molecular sponge of miR-224-5p to modulate fizzled 5 expression
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Oral Squamous Cell Carcinoma | Gene | 28093311 |
| MALAT1 | miR-224-5p | MMP14 | MMP14；MMP-14；MMP-X1；MT-MMP；MT-MMP 1；MT1-MMP；MT1MMP；MTMMP1；WNCHRS | details
GnRH signaling pathway
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We determined that MALAT1 promotes melanoma cells proliferation, invasion and migration by sponging miR-22. MiR-22 was decreased and acted as a tumor suppressor in melanoma, and MMP14 and Snail were the functional targets of miR-22. Furthermore, MALAT1 could modulate MMP14 and Snail by operating as a competing endogenous RNA (ceRNA) for miR-22.
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Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22
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Malignant Melanoma | Oncotarget | 27564100 |