| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| MALAT1 | miR-140 | ZO-1 | TJP1；ZO-1 | details
Adherens junction；Tight junction；Gap junction；Vibrio cholerae infection；Epithelial cell signaling in Helicobacter pylori infection；Salmonella infection
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details
Functionally, knockdown of MALAT1 resulted in an impairment and increased the permeability of BTB as well as decreased the expression of ZO-1, occludin and claudin-5 in GECs. Further, there was reciprocal repression between MALAT1 and miR-140, and miR-140 mediated the effects that MALAT1 knockdown exerted.
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details
Knockdown of long non-coding RNA MALAT1 increases the blood-tumor barrier permeability by up-regulating miR-140
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Blood-Tumor | Biochim Biophys Acta | 26619802 |
| PlncRNA1 | miR-34c | ZO-1 | TJP1；ZO-1 | details
Adherens junction；Tight junction；Gap junction；Vibrio cholerae infection；Epithelial cell signaling in Helicobacter pylori infection；Salmonella infection
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details
Tight junction (TJ) proteins ZO-1 and occludin were regulated by MAZ, while, miR-34c targeted MAZ to regulate its expression, in addition, PlncRNA1 and miR-34c bound together to regulate the expressions of MAZ, ZO-1 and occludin.
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details
MiR-34c and PlncRNA1 mediated the function of intestinal epithelial barrier by regulating tight junction proteins in inflammatory bowel disease
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Inflammatory Bowel Disease | Biochem Biophys Res Commun | 28153728 |