LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
MALAT1 miR-124 GRB2 GRB2;ASH;EGFRBP-GRB2;Grb3-3;MST084;MSTP084;NCKAP2 details
Pathways in cancer;Focal adhesion;MAPK signaling pathway;ErbB signaling pathway;Prostate cancer;Hepatitis C;Hepatitis B;Chemokine signaling pathway;PI3K-Akt signaling pathway;Dorso-ventral axis formation;Osteoclast differentiation;Chronic myeloid leukemia;Gap junction;Fc epsilon RI signaling pathway;Insulin signaling pathway;Renal cell carcinoma ;Endometrial cancer;Non-small cell lung cancer;Proteoglycans in cancer;Glioma;Estrogen signaling pathway;Viral carcinogenesis;Alcoholism;Jak-STAT signaling pathway;Neurotrophin signaling pathway;Natural killer cell mediated cytotoxicity;GnRH signaling pathway;T cell receptor signaling pathway;B cell receptor signaling pathway;Acute myeloid leukemia
details
Besides, knockdown of MALAT1 increased the expression of miRNA-124, while ectopic expression of miR-124 decreased MALAT1 expression. In addition, we also verified a direct interaction between miR-124 and 3'UTR of GRB2. MALAT1 can indirectly modulate GRB2 expression via competing miR-124.
details
MALAT1-miR-124-RBG2 axis is involved in growth and invasion of HR-HPV-positive cervical cancer cells
Cervical Cancer Tumour Biol 26242259
MALAT1 miR-124 GRB2 GRB2;ASH;EGFRBP-GRB2;Grb3-3;MST084;MSTP084;NCKAP2 details
PI3K-Akt signaling pathway;MAPK signaling pathway;ErbB signaling pathway;Alcoholism;Neurotrophin signaling pathway;Viral carcinogenesis;Acute myeloid leukemia;Estrogen signaling pathway;Chemokine signaling pathway;GnRH signaling pathway;Endometrial cancer;Prostate cancer;Dorso-ventral axis formation; Glioma;Non-small cell lung cancer;Chronic myeloid leukemia;Pathways in cancer;Proteoglycans in cancer;Osteoclast differentiation;Focal adhesion;Hepatitis B;Gap junction;Jak-STAT signaling pathway;Natural killer cell mediated cytotoxicity;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Hepatitis C; T cell receptor signaling pathway;Insulin signaling pathway;Renal cell carcinoma
details
In addition, we also verified a direct interaction between miR-124 and 3'UTR of GRB2. MALAT1 can indirectly modulate GRB2 expression via competing miR-124.
details
MALAT1-miR-124-RBG2 axis is involved in growth and invasion of HR-HPV-positive cervical cancer cells
Cervical Cancer Tumour Biol 26242259