LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
H19 let-7a IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
HULC let-7a IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
H19 let-7b IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
HULC let-7b IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
H19 miR-372 IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
HULC miR-372 IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
H19 miR-373 IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
HULC miR-373 IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
H19 and HULC functioned as competing endogenous RNAs (ceRNAs) by sponging let-7a/let-7b and miR-372/miR-373, respectively, which activate pivotal inflammation cytokine IL-6 and chemokine receptor CXCR4.
details
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Cholangiocarcinoma J Hematol Oncol 27809873
mmu_circRNA_007893 mmu-miR-485-5p IL-6 IL6;BSF2;HGF;HSF;IFNB2;IL-6 details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
details
Furthermore, when overexpression of mmu-miR-485-5p, IL-6 mRNA was markedly decreased. The results demonstrated that CGRP-induced IL-6 mRNA expression was mediated by mmu_circRNA_007893, and mmu_circRNA_007893 functioned as an endogenous mmu-miR-485-5p sponge as part of induction of IL-6 mRNA expression.
details
Calcitonin gene?related peptide induces IL?6 expression in RAW264.7 macrophages mediated by mmu_circRNA_007893
RAW264.7 macrophages Mol Med Rep 29039515
circ_0009910 miR-449a IL6R IL6R;CD126;IL-6R-1;IL-6RA;IL6Q;IL6RA;IL6RQ;gp80 details
Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage
details
Direct interaction of circ_0009910 and miR-449a was confirmed through dual-luciferase assays. Moreover, IL6R was predicted as a potential target of miR-449a. Overexpression of miR-449a decreased the mRNA and protein levels of IL6R.
details
Hsa_circ_0009910 promotes carcinogenesis by promoting the expression of miR-449a target IL6R in osteosarcoma
Osteosarcoma Biochem Biophys Res Commun 29117539