LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
lnc-ATB | miR-200b | Kindlin-2 | FERMT2;KIND2;MIG2;PLEKHC1;UNC112;UNC112B;mig-2 | details | details
Mechanistic investigation indicated that lnc-ATB exerted oncogenic activities via regulating Kindlin-2, as the anti-migration role of lnc-ATB silence was attenuated by ectopic expression of Kindlin-2. Further analysis showed that lnc-ATB functions as a molecular sponge for miR-200b and Kindlin-2.
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details
Long non-coding RNA ATB promotes malignancy of esophageal squamous cell carcinoma by regulating miR-200b/Kindlin-2 axis.
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Esophageal squamous cell carcinoma | Cell Death Dis | 28640252 |