LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
MEG3 | miR-140-5p | HDAC7 | HDAC7;HD7;HD7A;HDAC7A | details
Alcoholism;Viral carcinogenesis
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details
The luciferase reporter assay and RIP assay showed that MEG3 targeted miR-140-5p. In addition, the HDAC7 expression levels were regulated by miR-140-5p and MEG3.
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details
Pioglitazone up-regulates long non-coding RNA MEG3 to protect endothelial progenitor cells via increasing HDAC7 expression in metabolic syndrome
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Metabolic Syndrome | Biomed Pharmacother | 26898430 |
Unigene56159 | miR-140-5p | Slug | SNAI2;SLUG;SLUGH1;SNAIL2;WS2D | details
Hippo signaling pathway;Adherens junction
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details
Mechanistically, Unigene56159 could directly bind to miR-140-5p and effectively act as a competing endogenous RNA (ceRNA) for miR-140-5p to de-repress the expression of the target gene Slug.
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details
Long non-coding RNA Unigene56159 promotes epithelial-mesenchymal transition by acting as a ceRNA of miR-140-5p in hepatocellular carcinoma cells
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Hepatocellular Carcinoma | Cancer Lett | 27597739 |