LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
lnc133b miR-133b IGF1R IGF1R;CD221;IGFIR;IGFR;JTK13 details
Long-term depression;HIF-1 signaling pathway;Oocyte meiosis;Endocytosis;Prostate cancer;PI3K-Akt signaling pathway;Focal adhesion;Adherens junction;Ovarian steroidogenesis;Progesterone-mediated oocyte maturation;Pathways in cancer;Proteoglycans in cancer;Melanoma; Transcriptional misregulation in cancer;Glioma
details
The qRT-PCR results also showed that lnc133b negatively regulates miR-133b expression and a Western blot assay showed that lnc133b positively regulates IGF1R expression, indicating that the lnc133b/miR-133b/IGF1R axis is a potential pathway for promoting satellite cell proliferation and repressing their differentiation through the ceRNA mechanism. Building on the findings of previous reports, we constructed the lnc133b/miR-133b/FGFR1 & PP2AC pathway to improve the lnc133b regulation network regulating the proliferation and differentiation of satellite cells.
details
lnc133b, a novel, long non-coding RNA, regulates bovine skeletal muscle satellite cell proliferation and differentiation by mediating miR-133b.
Skeletal muscle satellite cell Gene 28757453
lnc133b miR-133b PP2AC PPP2CA;PP2Ac;PP2CA;PP2Calpha;RP-C details
mRNA surveillance pathway;Oocyte meiosis;PI3K-Akt signaling pathway;TGF-beta signaling pathway;Hippo signaling pathway; Tight junction;Dopaminergic synapse;Long-term depression;Chagas disease (American trypanosomiasis);Hepatitis C
details
The qRT-PCR results also showed that lnc133b negatively regulates miR-133b expression and a Western blot assay showed that lnc133b positively regulates IGF1R expression, indicating that the lnc133b/miR-133b/IGF1R axis is a potential pathway for promoting satellite cell proliferation and repressing their differentiation through the ceRNA mechanism. Building on the findings of previous reports, we constructed the lnc133b/miR-133b/FGFR1 & PP2AC pathway to improve the lnc133b regulation network regulating the proliferation and differentiation of satellite cells.
details
lnc133b, a novel, long non-coding RNA, regulates bovine skeletal muscle satellite cell proliferation and differentiation by mediating miR-133b.
Skeletal muscle satellite cell Gene 28757453