LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
FER1L4 | miR-106a-5p | PTEN | PTEN;10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1 | details
p53 signaling pathway;Inositol phosphate metabolism;Prostate cancer;Phosphatidylinositol signaling system;mTOR signaling pathway;PI3K-Akt signaling pathway;Focal adhesion;Tight junction;Hepatitis B;Pathways in cancer;Melanoma;Endometrial cancer;Glioma;Small cell lung cancer
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Here, we report that the lncRNA FER1L4 (fer-1-like family member 4, pseudogene) acts as a competing endogenous RNA (ceRNA) to regulate the expression of PTEN (a well-known tumor suppressor gene) by taking up miR-106a-5p in gastric cancer.
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Long noncoding RNA FER1L4 suppresses cancer cell growth by acting as a competing endogenous RNA and regulating PTEN expression
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Cancer Cell Growth | Sci Rep | 26306906 |