LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
UCA1 miR-196a-5p CREB CREB1;CREB details
Dopaminergic synapse;PI3K-Akt signaling pathway;HTLV-I infection;Huntington's disease;Hepatitis B;Osteoclast differentiation;Antigen processing and presentation;Circadian rhythm;Alcoholism;Circadian entrainment;Cholinergic synapse;Prostate cancer;Viral carcinogenesis;Cocaine addiction;Tuberculosis;Insulin secretion;Estrogen signaling pathway;Melanogenesis;Amphetamine addiction;Vasopressin-regulated water reabsorption
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Moreover, UCA1 activated transcription factor CREB which led to miR-196a-5p expression by binding with its promoter. miR-196a-5p induction is involved in UCA1 inhibition of apoptosis induced by cisplatin/gemcitabine via targeting p27Kip1
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Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells
Bladder Cancer Cancer Lett 27591936