LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
H19 miR-140 iASPP PPP1R13L;IASPP;NKIP1;RAI;RAI4 details
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In addition, miR-140 dependent inhibitor of apoptosis-stimulating protein of p53 (iASPP) regulation was required in H19 induced glioma cell growth.
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The lncRNA H19 interacts with miR-140 to modulate glioma growth by targeting iASPP
Glioma Arch Biochem Biophys 27693036
MALAT1 miR-140 ZO-1 TJP1;ZO-1 details
Adherens junction;Tight junction;Gap junction;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Salmonella infection
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Functionally, knockdown of MALAT1 resulted in an impairment and increased the permeability of BTB as well as decreased the expression of ZO-1, occludin and claudin-5 in GECs. Further, there was reciprocal repression between MALAT1 and miR-140, and miR-140 mediated the effects that MALAT1 knockdown exerted.
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Knockdown of long non-coding RNA MALAT1 increases the blood-tumor barrier permeability by up-regulating miR-140
Blood-Tumor Biochim Biophys Acta 26619802