LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
H19 | miR-140 | iASPP | PPP1R13L;IASPP;NKIP1;RAI;RAI4 | details | details
In addition, miR-140 dependent inhibitor of apoptosis-stimulating protein of p53 (iASPP) regulation was required in H19 induced glioma cell growth.
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details
The lncRNA H19 interacts with miR-140 to modulate glioma growth by targeting iASPP
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Glioma | Arch Biochem Biophys | 27693036 |
MALAT1 | miR-140 | ZO-1 | TJP1;ZO-1 | details
Adherens junction;Tight junction;Gap junction;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Salmonella infection
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details
Functionally, knockdown of MALAT1 resulted in an impairment and increased the permeability of BTB as well as decreased the expression of ZO-1, occludin and claudin-5 in GECs. Further, there was reciprocal repression between MALAT1 and miR-140, and miR-140 mediated the effects that MALAT1 knockdown exerted.
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details
Knockdown of long non-coding RNA MALAT1 increases the blood-tumor barrier permeability by up-regulating miR-140
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Blood-Tumor | Biochim Biophys Acta | 26619802 |