LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
TUG1 | miR-144 | c-Met | MET;AUTS9;DFNB97;HGFR;RCCP2;c-Met | details
HIF-1 signaling pathway;NF-kappa B signaling pathway;Protein processing in endoplasmic reticulum;Pathways in cancer;Small cell lung cancer;Prostate cancer;PI3K-Akt signaling pathway;Apoptosis;Focal adhesion; Neurotrophin signaling pathway;Cholinergic synapse;Amyotrophic lateral sclerosis (ALS);Colorectal cancer;Hepatitis B;Epstein-Barr virus infection; Toxoplasmosis;Tuberculosis
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The results of qRT-PCR and western-blot proved that the expression of microRNA-144 was significantly boosted and the expression level of c-Met mRNA and protein was inhibited after lncRNA-TUG1 was silenced
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Inhibition of long non-coding RNA TUG1 on gastric cancer cell transference and invasion through regulating and controlling the expression of miR-144/c-Met axis
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Gastric Cancer | Asian Pac J Trop Med | 27261864 |
TUG1 | miR-144 | HSF2 | HSF2;HSF 2;HSTF 2 | details | details
Furthermore, Knockdown of TUG1 also down-regulated Heat shock transcription factor 2 (HSF2), a transcription factor of the heat shock transcription factor family, which was defined as a direct and functional downstream target of miR-144.
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The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144
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Blood-Tumor | Oncotarget | 26078353 |