LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
lnc133b miR-133b IGF1R IGF1R;CD221;IGFIR;IGFR;JTK13 details
Long-term depression;HIF-1 signaling pathway;Oocyte meiosis;Endocytosis;Prostate cancer;PI3K-Akt signaling pathway;Focal adhesion;Adherens junction;Ovarian steroidogenesis;Progesterone-mediated oocyte maturation;Pathways in cancer;Proteoglycans in cancer;Melanoma; Transcriptional misregulation in cancer;Glioma
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The qRT-PCR results also showed that lnc133b negatively regulates miR-133b expression and a Western blot assay showed that lnc133b positively regulates IGF1R expression, indicating that the lnc133b/miR-133b/IGF1R axis is a potential pathway for promoting satellite cell proliferation and repressing their differentiation through the ceRNA mechanism. Building on the findings of previous reports, we constructed the lnc133b/miR-133b/FGFR1 & PP2AC pathway to improve the lnc133b regulation network regulating the proliferation and differentiation of satellite cells.
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lnc133b, a novel, long non-coding RNA, regulates bovine skeletal muscle satellite cell proliferation and differentiation by mediating miR-133b.
Skeletal muscle satellite cell Gene 28757453
MALAT1 miR-122 IGF-1R IGF1R;CD221;IGFIR;IGFR;JTK13 details
Adherens junction;HIF-1 signaling pathway;Oocyte meiosis;Endocytosis;PI3K-Akt signaling pathway;Focal adhesion;Prostate cancer;Long-term depression;Ovarian steroidogenesis;Proteoglycans in cancer;Glioma;Progesterone-mediated oocyte maturation;Pathways in cancer;Melanoma;Transcriptional misregulation in cancer
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Furthermore, the miR-122-IGF-1R signaling correlated with the dysregulated MALAT1 expression in gastric cancer.
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The lncRNA MALAT1 is a novel biomarker for gastric cancer metastasis
Gastric Cancer Oncotarget 27486823