| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| H19 | miR-675 | HDAC | HDAC9；HD7；HD7b；HD9；HDAC；HDAC7；HDAC7B；HDAC9B；HDAC9FL；HDRP；MITR | details | details
Overexpression of H19 and miR-675 inhibited adipogenesis, while knockdown of their endogenous expression accelerated adipogenic differentiation. Mechanistically, we found that miR-675 targeted the 3' untranslated regions of the histone deacetylase (HDAC) 4-6 transcripts and resulted in deregulation of HDACs 4-6, essential molecules in adipogenesis.
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details
Long Non-coding RNA H19 Inhibits Adipocyte Differentiation of Bone Marrow Mesenchymal Stem Cells through Epigenetic Modulation of Histone Deacetylases
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Bone Marrow Mesenchymal Stem Cells | Sci Rep | 27349231 |
| MEG3 | miR-140-5p | HDAC7 | HDAC7；HD7；HD7A；HDAC7A | details
Alcoholism；Viral carcinogenesis
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details
The luciferase reporter assay and RIP assay showed that MEG3 targeted miR-140-5p. In addition, the HDAC7 expression levels were regulated by miR-140-5p and MEG3.
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Pioglitazone up-regulates long non-coding RNA MEG3 to protect endothelial progenitor cells via increasing HDAC7 expression in metabolic syndrome
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Metabolic Syndrome | Biomed Pharmacother | 26898430 |