LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
NEAT1 miR-377-3p E2F3 E2F3;E2F-3 details
Glioma;Cell cycle;Hepatitis B;HTLV-I infection;Pathways in cancer;Pancreatic cancer;Prostate cancer;Melanoma;Bladder cancer;Non-small cell lung cancer; Chronic myeloid leukemia;Small cell lung cancer
details
Additionally, by using bioinformatics study and RNA pull down combined with luciferase reporter assays, we demonstrated that NEAT1 functioned as a competing endogenous RNA (ceRNA) for hsa-miR-377-3p, antagonized its functions and led to the de-repression of its endogenous targets E2F3, which was a core oncogene in promoting NSCLC progression.
details
Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway
Non-Small Cell Lung Cancer Oncotarget 27351135