Cholinergic synapse；HIF-1 signaling pathway；Chemokine signaling pathway；MAPK signaling pathway；Small cell lung cancer；Toll-like receptor signaling pathway；Fc epsilon RI signaling pathway；T cell receptor signaling pathway；ErbB signaling pathway；Carbohydrate digestion and absorption；Chagas disease (American trypanosomiasis)；mTOR signaling pathway；PI3K-Akt signaling pathway；Hepatitis B；HTLV-I infection；Pathways in cancer；Toxoplasmosis；Colorectal cancer；Endometrial cancer；Jak-STAT signaling pathway；Neurotrophin signaling pathway；Influenza A；Proteoglycans in cancer； Measles；Dopaminergic synapse；Tuberculosis；Prostate cancer；Non-small cell lung cancer；Apoptosis；Progesterone-mediated oocyte maturation；Melanoma；Chronic myeloid leukemia； B cell receptor signaling pathway； Insulin signaling pathway；Renal cell carcinoma；Estrogen signaling pathway；VEGF signaling pathway；Osteoclast differentiation；Glioma；Epstein-Barr virus infection； Focal adhesion；Tight junction；Hepatitis C；Fc gamma R-mediated phagocytosis；Pancreatic cancer；Acute myeloid leukemia；Adipocytokine signaling pathway

Collectively, our findings established Linc00152 as a candidate prognostic indicator of outcome and drug responsiveness in colon cancer patients, and the involvement of competing endogenous RNAs mechanism in Linc00152/miR-193a-3p/ERBB4/AKT signaling axis may provide a novel choice in the investigation of drug resistance.

Linc00153 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer

ErbB signaling pathway；Calcium signaling pathway；Endocytosis；Proteoglycans in cancer

Collectively, our findings established Linc00152 as a candidate prognostic indicator of outcome and drug responsiveness in colon cancer patients, and the involvement of competing endogenous RNAs mechanism in Linc00152/miR-193a-3p/ERBB4/AKT signaling axis may provide a novel choice in the investigation of drug resistance.

Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer

Neurotrophin signaling pathway

Meanwhile, we discovered that LINC00052 could regulate NTRK3 expression by forming complementary base pairing with miR-128 and miR-485-3p to reduce the luciferase activity of NTRK3 3'UTR.

LINC00052 regulates the expression of NTRK3 by miR-128 and miR-485-3p to strengthen HCC cells invasion and migration

Neurotrophin signaling pathway

Meanwhile, we discovered that LINC00052 could regulate NTRK3 expression by forming complementary base pairing with miR-128 and miR-485-3p to reduce the luciferase activity of NTRK3 3'UTR.

LINC00052 regulates the expression of NTRK3 by miR-128 and miR-485-3p to strengthen HCC cells invasion and migration