LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
hsa_circ_0012673 | miR-22 | ErbB3 | ERBB3;ErbB-3;HER3;LCCS2;MDA-BF-1;c-erbB-3;c-erbB3;erbB3-S;p180-ErbB3;p45-sErbB3;p85-sErbB3 | details
ErbB signaling pathway;Calcium signaling pathway;Endocytosis;Proteoglycans in cancer
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Furthermore, hsa_circ_0012673 was primarily localized in the cytoplasm and promoted cell proliferation of LAC cells by sponging miR-22, which targeted erb-b2 receptor tyrosine kinase 3 (ErbB3) in LAC. Hsa_circ_0012673 promotes LAC proliferation by suppressing miR-22, which targets ErbB3.
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Increased circular RNA hsa_circ_0012673 acts as a sponge of miR-22 to promote lung adenocarcinoma proliferation
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Lung adenocarcinoma | Biochem Biophys Res Commun | 29366790 |
SIRT1 AS | miR-22 | SIRT1 | SIRT1;SIR2;SIR2L1;Hsir2 | details
Amphetamine addiction
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Our data suggest that SIRT1 AS lncRNA relieves miR-22-induced SIRT1 downregulation by competitively sponging miR-22.
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NAMPT regulates senescence, proliferation, and migration of endothelial progenitor cells through the SIRT1 AS lncRNA/miR-22/SIRT1 pathway
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Cardiovascular Diseases | Biochem Biophys Res Commun | 27569277 |