LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
p21 | miR-181b | PTEN | PTEN;10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1 | details
p53 signaling pathway;Inositol phosphate metabolism;Prostate cancer;Phosphatidylinositol signaling system;mTOR signaling pathway;PI3K-Akt signaling pathway;Focal adhesion;Tight junction;Hepatitis B;Pathways in cancer;Melanoma;Endometrial cancer;Glioma;Small cell lung cancer
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The effects of lincRNA-p21 on PTEN expression and HSC activation were inhibited by miR-181b mimics. We demonstrated that lincRNA-p21 enhanced PTEN expression by competitively binding miR-181b.
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Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis
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Liver Fibrosis | Mediators Inflamm | 27610008 |