LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
NEAT1 | miR-449b-5p | BCL2 | BCL2;Bcl-2;PPP1R50 | details
HIF-1 signaling pathway;NF-kappa B signaling pathway;Protein processing in endoplasmic reticulum;Pathways in cancer;Small cell lung cancer;Prostate cancer;PI3K-Akt signaling pathway;Apoptosis;Focal adhesion; Neurotrophin signaling pathway;Cholinergic synapse;Amyotrophic lateral sclerosis (ALS);Colorectal cancer;Hepatitis B;Epstein-Barr virus infection; Toxoplasmosis;Tuberculosis
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Furthermore, we verified that c-Met was a directly target of miR-449b-5p. Rescue assays demonstrated NEAT1 functions a molecular sponge for miR-449b-5p and leads to the upregulation of c-Met.
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Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis
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Glioma | Tumour Biol | 26242266 |