LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
PVT1 | miR-195 | FASN | FASN;FAS;OA-519;SDR27X1 | details
Fatty acid biosynthesis;Metabolic pathways; Insulin signaling pathway
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Moreover, silencing PVT1 by siRNA inhibited BCL2, CCND1, and FASN protein expression via miR-195 in osteosarcoma cells, and BCL2 inhibited the si-PVT1#1-induced apoptosis of U2OS cells.
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Long non-coding RNA PVT1 promotes osteosarcoma development by acting as a molecular sponge to regulate miR-195
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Osteosarcoma | Oncotarget | 27813492 |