| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| HIF1A-AS2 | miR-153-3p | HIF-1alpha | HIF1A；HIF-1A；HIF-1alpha；HIF1；HIF1-ALPHA；MOP1；PASD8；bHLHe78 | details
HIF-1 signaling pathway；mTOR signaling pathway；Pathways in cancer；Proteoglycans in cancer；Renal cell carcinoma
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details
HIF1A-AS2 was up-regulated in HUVECs in hypoxia. Luciferase reporter assay indicated that HIF1A-AS2 serves as a 'sponge' to miR-153-3p, which decreased the post-transcriptional silencing of HIF-1α by miR-153-3p.
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details
lncRNAs HIF1A-AS2 facilitates the up-regulation of HIF-1α by sponging to miR-153-3p, whereby promoting angiogenesis in HUVECs in hypoxia.
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Human umbilical vein endothelial cells | Biomed Pharmacother | 28985553 |
| PVT1 | miR-186 | HIF-1alpha | HIF1A；HIF-1A；HIF-1alpha；HIF1；HIF1-ALPHA；MOP1；PASD8；bHLHe78 | details
HIF-1 signaling pathway；mTOR signaling pathway；Pathways in cancer；Proteoglycans in cancer；Renal cell carcinoma
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details
In addition, PVT1 could directly interact with miR-186 in GC cells and this interaction lead to the inhibition of downstream of HIF-1α expression.
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The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancer
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Gastric Cancer | Biomed Pharmacother | 28122299 |
| UCA1 | miR-18a | HIF-1alpha | HIF1A；HIF-1A；HIF-1alpha；HIF1；HIF1-ALPHA；MOP1；PASD8；bHLHe78 | details
HIF-1 signaling pathway；mTOR signaling pathway；Pathways in cancer；Proteoglycans in cancer；Renal cell carcinoma
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details
The upregulated UCA1 sponges miR-18a, which is a negative regulator of HIF1α. Therefore, UCA1 upregulation is further enhanced through a miR-18a-HIF1α feedback loop.
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Long non-coding RNA UCA1 enhances tamoxifen resistance in breast cancer cells through a miR-18a-HIF1α feedback regulatory loop
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Breast Cancer | Tumour Biol | 27629141 |