LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
CCAT1 | miR-218 | BMI1 | BMI1;FLVI2/BMI1;PCGF4;RNF51 | details
Transcriptional misregulation in cancer
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This epigenetic silencing of miR-218 by CCAT1 induces an altered cell cycle transition through BMI1 and provides a new mechanism for CSE-induced lung carcinogenesis.
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Epigenetic silencing of miR-218 by the lncRNA CCAT1, acting via BMI1, promotes an altered cell cycle transition in the malignant transformation of HBE cells induced by cigarette smoke extract
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Lung Cancer | Toxicol Appl Pharmacol | 27212446 |