Toll-like receptor signaling pathway；Apoptosis；NF-kappa B signaling pathway；Salmonella infection；Pertussis；Legionellosis；Leishmaniasis；Chagas disease (American trypanosomiasis)；Measles；African trypanosomiasis；Tuberculosis；Influenza A；Herpes simplex infection； Malaria；Hepatitis B；Toxoplasmosis

Moreover, the up-regulated lncRNA cardiac hypertrophy-related factor (CHRF) reversed the inhibitory effect of miR-489 on MyD88 and Smad3 and then triggered the inflammation and fibrotic signaling pathways.

miR-489 inhibits silica-induced pulmonary fibrosis by targeting MyD88 and Smad3 and is negatively regulated by lncRNA CHRF