LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
NEAT1 | miR-548 | FUS | FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;TLS | details
Transcriptional misregulation in cancer
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In addition, the RNA-binding protein fused in sarcoma/translocated in liposarcoma (FUS/TLS) physically interacted with NEAT1, and reducing the expression of FUS/TLS also induced cell apoptosis. Multiple miRNAs were identified as regulators of NEAT1, but only overexpression of miR-548ar was able to decrease NEAT1 expression and promote apoptosis.
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NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548
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Breast Cancer | Gene Regul Syst Bio | 27147820 |