LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
H19 | miR-194-5p | AKT2 | AKT2;:HIHGHH;PKBB;PKBBETA;PRKBB;RAC-BETA | details
Dopaminergic synapse;ErbB signaling pathway;MAPK signaling pathway;Prostate cancer;Pathways in cancer;Melanoma;Pancreatic cancer;Chemokine signaling pathway;Fc epsilon RI signaling pathway;HIF-1 signaling pathway;Progesterone-mediated oocyte maturation;Colorectal cancer;HTLV-I infection;mTOR signaling pathway;Toll-like receptor signaling pathway;Toxoplasmosis;Epstein-Barr virus infection;Proteoglycans in cancer;Influenza A;Cholinergic synapse;Fc gamma R-mediated phagocytosis;Neurotrophin signaling pathway;Jak-STAT signaling pathway;T cell receptor signaling pathway;Acute myeloid leukemia;Glioma;Small cell lung cancer;Non-small cell lung cancer;PI3K-Akt signaling pathway; Apoptosis;VEGF signaling pathway;Hepatitis C;Carbohydrate digestion and absorption;Chagas disease (American trypanosomiasis);Measles;Adipocytokine signaling pathway;Tuberculosis; Osteoclast differentiation;B cell receptor signaling pathway;Hepatitis B;Focal adhesion;Estrogen signaling pathway;Insulin signaling pathway;Tight junction;Endometrial cancer;Chronic myeloid leukemia;Renal cell carcinoma
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In addition, overexpression of H19 in GBC-SD cells downregulated miR-194-5p and markedly increased AKT2 expression, and miR-194-5p mimic reversed these effects.
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Long noncoding RNA H19 contributes to gallbladder cancer cell proliferation by modulated miR-194-5p targeting AKT2
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Gallbladder Cancer | Tumour Biol | 26803515 |