NF-kappa B signaling pathway；Apoptosis；Toll-like receptor signaling pathway；RIG-I-like receptor signaling pathway；Cytosolic DNA-sensing pathway；Hepatitis C；Epstein-Barr virus infection

In exploring the molecular mechanism by which miR-873 expression is regulated, we identify NRF as an endogenous sponge RNA and repress miR-873 expression. NRF directly binds to miR-873 and regulates RIPK1/RIPK3 expression and necrosis.

The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873