LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
HOTAIRM1 miR-3960 B7H2 ICOSLG;B7-H2;B7H2;B7RP-1;B7RP1;CD275;GL50;ICOS-L;ICOSL;LICOS details
Cell adhesion molecules (CAMs);Intestinal immune network for IgA production
details
Mechanistically, we found that the silencing of HOTAIRM1 caused changes in the expression of several monocyte differentiation markers such as CD14 and B7H2. In addition, based on the "competing endogenous RNA" hypothesis, we discovered miR-3960 targeting both HOTAIRM1 and the DC differentiation repression gene, HOXA1, by most possibly constructing a potential competing endogenous RNA network.
details
Downregulation of long noncoding RNA HOTAIRM1 promotes monocyte/dendritic cell differentiation through competitively binding to endogenous miR-3960
Hematopoiesis Onco Targets Ther 28280365
HOTAIRM1 miR-3960 CD14 details
Hematopoietic cell lineage;MAPK signaling pathway;NF-kappa B signaling pathway;Phagosome;Toll-like receptor signaling pathway;Tuberculosis;Transcriptional misregulation in cancer;Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Salmonella infection; Pertussis;Legionellosis;Amoebiasis
details
Mechanistically, we found that the silencing of HOTAIRM1 caused changes in the expression of several monocyte differentiation markers such as CD14 and B7H2. In addition, based on the "competing endogenous RNA" hypothesis, we discovered miR-3960 targeting both HOTAIRM1 and the DC differentiation repression gene, HOXA1, by most possibly constructing a potential competing endogenous RNA network.
details
Downregulation of long noncoding RNA HOTAIRM1 promotes monocyte/dendritic cell differentiation through competitively binding to endogenous miR-3960
Hematopoiesis Onco Targets Ther 28280365