LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
GAS5 | miR-103 | mTOR | MTOR;FRAP;FRAP1;FRAP2;RAFT1;RAPT1 | details
HIF-1 signaling pathway;ErbB signaling pathway;mTOR signaling pathway;PI3K-Akt signaling pathway;Insulin signaling pathway;Adipocytokine signaling pathway;Type II diabetes mellitus;Pathways in cancer;Proteoglycans in cancer;Acute myeloid leukemia; Glioma;Prostate cancer
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The exposure levels of the proteins related to the protein kinase B (AKT)/mammalian target of rapamycin (mTOR) axis, including AKT, mTOR, and S6K1, were measured by western blot PC3 cells infected with lncRNA GAS5 mimic; lncRNA GAS5 siRNA; or a combination of lncRNA and miR-103.
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LncRNA GAS5 inhibits proliferation and progression of prostate cancer by targeting miR-104 through AKT/mTOR signaling pathway
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Prostate Cancer | Tumour Biol | 27743383 |