| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| MALAT1 | miR-22-3p | CXCR2 | CXCR2；CD182；CDw128b；CMKAR2；IL8R2；IL8RA；IL8RB | details
Cytokine-cytokine receptor interaction；Chemokine signaling pathway；Endocytosis；Epithelial cell signaling in Helicobacter pylori infection
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details
MALAT1 silencing significantly downregulated the expression of the miR-22-3p target gene CXCR2 via reversing the effect of the miR-22-3p, resulting in the aggravation of Oxidized low-density lipoprotein (ox-LDL)-induced endothelial injury； this process was associated with the AKT pathway.
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The lncRNA MALAT1 protects the endothelium against ox-LDL-induced dysfunction via upregulating the expression of the miR-22-3p target genes CXCR2 and AKT
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Kidney Carcinoma | FEBS Lett | 26364720 |