LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
RP11-838N2.4 | miR-10a | EphA8 | EPHA8;EEK;EK3;HEK3 | details
Axon guidance
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Moreover, lncRNA RP11-838N2.4 acts as an endogenous sponge, suppressing the function of miR-10a through conserved sequences and increasing the expression of EphA8 that enhanced the rate of cell apoptosis, thereby intensified sensitivity of GBM cells to TMZ.
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Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines
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Glioblastoma | Oncotarget | 27270310 |