LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
ROR miR-145 Sox2 SOX2;ANOP3;MCOPS3 details
Hippo signaling pathway
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The experimental results indicate that lncRNA-ROR effectively maintains Sox2 gene expression through competitive binding to miR-145, achieving pluripotency maintenance in HuAECs and regulation of their directed β islet-like cell differentiation efficiency.
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miR-145 modulates lncRNA-ROR and Sox2 expression to maintain human amniotic epithelial stem cell pluripotency and β islet-like cell differentiation efficiency
Human Amniotic Epithelial Stem Cells Gene 27346547
SOX2OT miR-211 SOX2 SOX2;ANOP3;MCOPS3 details
Hippo signaling pathway
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From the list of potential candidate miRNAs, miR-211 was found to have complementary sequences to SOX2OT and SOX2 transcripts.
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Down-Regulatory Effects of miR-211 on Long Non-Coding RNA SOX2OT and SOX2 Genes in Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma Cell J 26862518
HOTAIR miR-34a Sox2 SOX2;ANOP3;MCOPS3 details
Hippo signaling pathway
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Moreover, full-length HOTAIR transcriptionally inhibits miR-34a specifically, leading to upregulation of Sox2, which is targeted by miR-34a.
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Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells
Breast Cancer PLoS One 28122024