LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
HOTAIR | miR-331-3p | HER2 | ERBB2;CD340;HER-2;HER-2/neu;HER2;MLN 19;NEU;NGL;TKR1 | details
Pathways in cancer;ErbB signaling pathway;Calcium signaling pathway;HIF-1 signaling pathway;Focal adhesion;Adherens junction;Proteoglycans in cancer;Non-small cell lung cancer;Pancreatic cancer;Endometrial cancer;Prostate cancer;Bladder cancer
|
details
In particular, HOTAIR may act as a ceRNA, effectively becoming a sink for miR-331-3p, thereby modulating the derepression of HER2 and imposing an additional level of post-transcriptional regulation.
|
details
Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer
|
Gastric Cancer | Mol Cancer | 24775712 |