LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
HOTAIR miR-331-3p HER2 ERBB2;CD340;HER-2;HER-2/neu;HER2;MLN 19;NEU;NGL;TKR1 details
Pathways in cancer;ErbB signaling pathway;Calcium signaling pathway;HIF-1 signaling pathway;Focal adhesion;Adherens junction;Proteoglycans in cancer;Non-small cell lung cancer;Pancreatic cancer;Endometrial cancer;Prostate cancer;Bladder cancer
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In particular, HOTAIR may act as a ceRNA, effectively becoming a sink for miR-331-3p, thereby modulating the derepression of HER2 and imposing an additional level of post-transcriptional regulation.
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Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer
Gastric Cancer Mol Cancer 24775712