LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
CircVMA21 | miR-200c | XIAP | XIAP;API3;BIRC4;IAP-3;ILP1;MIHA;XLP2;hIAP-3;hIAP3 | details
NF-kappa B signaling pathway;Ubiquitin mediated proteolysis;Apoptosis;Focal adhesion;Toxoplasmosis;HTLV-I infection;Pathways in cancer;Small cell lung cancer
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CircVMA21 could alleviate inflammatory cytokines-induced NP cell apoptosis and imbalance between anabolism and catabolism of extracellular matrix through miR-200c-XIAP pathway. It provides a potentially effective therapeutic strategy for IVDD.
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Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein
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Intervertebral disc degeneration | Ann Rheum Dis | 29343508 |
Circ_0005015 | miR-519d-3p | XIAP | XIAP;API3;BIRC4;IAP-3;ILP1;MIHA;XLP2;hIAP-3;hIAP3 | details
NF-kappa B signaling pathway;Ubiquitin mediated proteolysis;Apoptosis;Focal adhesion;Toxoplasmosis;HTLV-I infection;Pathways in cancer;Small cell lung cancer
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details
Circ_0005015 acted as miR-519d-3p sponge to inhibit miR-519d-3p activity, leading to increased MMP-2, XIAP, and STAT3 expression.
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Identification and Characterization of Circular RNAs as a New Class of Putative Biomarkers in Diabetes Retinopathy
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Diabetes Retinopathy | Invest Ophthalmol Vis Sci | 29288268 |