HIF-1 signaling pathway； MAPK signaling pathway； Endometrial cancer；Glioma；ErbB signaling pathway；Calcium signaling pathway；Cytokine-cytokine receptor interaction；Proteoglycans in cancer；Prostate cancer；Endocytosis；GnRH signaling pathway；PI3K-Akt signaling pathway；Dorso-ventral axis formation；Non-small cell lung cancer；Pancreatic cancer；Melanoma；Bladder cancer；Focal adhesion；Hepatitis C；Adherens junction；Gap junction；Epithelial cell signaling in Helicobacter pylori infection；Regulation of actin cytoskeleton；Pathways in cancer；Estrogen signaling pathway

Moreover, as exhibited by luciferase reporter gene assays, miR-133a bound to XIST and the 3'UTR of EGFR by direct targeting.

LncRNA XIST Promotes Pancreatic Cancer Proliferation through miR-133a/EGFR

Pathways in cancer；Focal adhesion；MAPK signaling pathway；ErbB signaling pathway；Prostate cancer；Hepatitis C；Hepatitis B；Chemokine signaling pathway；PI3K-Akt signaling pathway；Dorso-ventral axis formation；Osteoclast differentiation；Chronic myeloid leukemia；Gap junction；Fc epsilon RI signaling pathway；Insulin signaling pathway；Renal cell carcinoma ；Endometrial cancer；Non-small cell lung cancer；Proteoglycans in cancer；Glioma；Estrogen signaling pathway；Viral carcinogenesis；Alcoholism；Jak-STAT signaling pathway；Neurotrophin signaling pathway；Natural killer cell mediated cytotoxicity；GnRH signaling pathway；T cell receptor signaling pathway；B cell receptor signaling pathway；Acute myeloid leukemia

Besides, knockdown of MALAT1 increased the expression of miRNA-124, while ectopic expression of miR-124 decreased MALAT1 expression. In addition, we also verified a direct interaction between miR-124 and 3'UTR of GRB2. MALAT1 can indirectly modulate GRB2 expression via competing miR-124.

MALAT1-miR-124-RBG2 axis is involved in growth and invasion of HR-HPV-positive cervical cancer cells

PI3K-Akt signaling pathway；MAPK signaling pathway；ErbB signaling pathway；Alcoholism；Neurotrophin signaling pathway；Viral carcinogenesis；Acute myeloid leukemia；Estrogen signaling pathway；Chemokine signaling pathway；GnRH signaling pathway；Endometrial cancer；Prostate cancer；Dorso-ventral axis formation； Glioma；Non-small cell lung cancer；Chronic myeloid leukemia；Pathways in cancer；Proteoglycans in cancer；Osteoclast differentiation；Focal adhesion；Hepatitis B；Gap junction；Jak-STAT signaling pathway；Natural killer cell mediated cytotoxicity；Fc epsilon RI signaling pathway；B cell receptor signaling pathway；Hepatitis C； T cell receptor signaling pathway；Insulin signaling pathway；Renal cell carcinoma

In addition, we also verified a direct interaction between miR-124 and 3'UTR of GRB2. MALAT1 can indirectly modulate GRB2 expression via competing miR-124.

MALAT1-miR-124-RBG2 axis is involved in growth and invasion of HR-HPV-positive cervical cancer cells