LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
CCAT1 miR-7 SPRY4 SPRY4;HH17 details
Jak-STAT signaling pathway
details
Mechanistic investigations found that CCAT1 could serve as a scaffold for two distinct epigenetic modification complexes (5? domain of CCAT1 binding Polycomb Repressive Complex 2 (PRC2) while 3? domain of CCAT1 binding SUV39H1) and modulate the histone methylation of promoter of SPRY4 (sprouty RTK signaling antagonist 4) in nucleus
details
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma
Esophageal Squamous Cell Carcinoma Nucleic Acids Res 27956498