LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
CCAT1 | miR-7 | SPRY4 | SPRY4;HH17 | details
Jak-STAT signaling pathway
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Mechanistic investigations found that CCAT1 could serve as a scaffold for two distinct epigenetic modification complexes (5? domain of CCAT1 binding Polycomb Repressive Complex 2 (PRC2) while 3? domain of CCAT1 binding SUV39H1) and modulate the histone methylation of promoter of SPRY4 (sprouty RTK signaling antagonist 4) in nucleus
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H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma
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Esophageal Squamous Cell Carcinoma | Nucleic Acids Res | 27956498 |