LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
HOTAIR | miR-1 | FOXC1 | FOXC1;ARA;FKHL7;FREAC-3;FREAC3;IGDA;IHG1;IRID1;RIEG3 | details | details
Taken together, these results suggest that HOTAIR is a FOXC1-activated driver of malignancy, which acts in part through the repression of miR-1.
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details
HOTAIR, a long non-coding RNA driver of malignancy whose expression is activated by FOXC1, negatively regulates miRNA-1 in hepatocellular carcinoma
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Hepatocellular Carcinoma | Oncol Lett | 27895772 |
XIST | miR-137 | FOXC1 | FOXC1;ARA;FKHL7;FREAC-3;FREAC3;IGDA;IHG1;IRID1;RIEG3 | details | details
The analysis of the mechanism of action revealed that the reduction of XIST inhibited the expression of the transcription factor forkhead box C1 (FOXC1) and zonula occludens 2 (ZO-2) by upregulating miR-137.
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details
Knockdown of long non-coding RNA XIST increases blood-tumor barrier permeability and inhibits glioma angiogenesis by targeting miR-137
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Glioma | Oncogenesis | 28287613 |