LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
MALAT1 | miR-448 | KDM5B | KDM5B;CT31;JARID1B;PLU-1;PLU1;PPP1R98;PUT1;RBBP2H1A | details | details
KDM5B-silencing in the TNBC cells correlated with the upregulation of hsa-miR-448 and led to suppression of MALAT1 expression with decreased migration, invasion and clonogenic capacity in vitro, as well as, poor survival in vivo.
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Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
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Breast Cancer | BMC Cancer | 26917489 |