| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| MALAT1 | miR-155 | FBXW7 | FBXW7；AGO；CDC4；FBW6；FBW7；FBX30；FBXO30；FBXW6；SEL-10；SEL10；hAgo；hCdc4 | details
Ubiquitin mediated proteolysis
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Further, MALAT1 suppresses cell viability by down-regulating miR-155. FBXW7 mRNA was identified as a direct target of miR-155 in glioma. The miR-155-induced tumorigenesis is mediated through FBXW7 function. Finally, we found that MALAT1 positively regulated FBXW7 expression, which was responsible for glioma progression mediated by MALAT1-miR-155 pathway.
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Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by suppressing miR-155 expression and activating FBXW7 function
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Glioma | Am J Cancer Res | 27904771 |