LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
XIST | miR-34a-5p | E2F3 | E2F3;E2F-3 | details
Glioma;Cell cycle;Hepatitis B;HTLV-I infection;Pathways in cancer;Pancreatic cancer;Prostate cancer;Melanoma;Bladder cancer;Non-small cell lung cancer; Chronic myeloid leukemia;Small cell lung cancer
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Additionally, mechanistic analysis revealed that XIST up-regulated the expression of miR-34a-5p targeted gene E2F3 through acting as a competitive 'sponge' of miR-34a-5p.
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Long non-coding RNA XIST exerts oncogenic functions in human nasopharyngeal carcinoma by targeting miR-34a-5p
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Nasopharyngeal Carcinoma | Gene | 27461945 |
TUG1 | miR-34a-5p | VEGFA | VEGFA;MVCD1;VEGF;VPF | details
HIF-1 signaling pathway;Cytokine-cytokine receptor interaction;mTOR signaling pathway;PI3K-Akt signaling pathway; VEGF signaling pathway;Focal adhesion; Pathways in cancer;Proteoglycans in cancer;Renal cell carcinoma;Pancreatic cancer;Bladder cancer;Rheumatoid arthritis
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TUG1 knockdown inhibits tumor growth and angiogenesis in vivo, and decreases hepatoblastoma cell viability, proliferation, migration, and invasion in vitro. TUG1, miR-34a-5p, and VEGFA constitutes to a regulatory network, and participates in regulating hepatoblastoma cell function, tumor progression, and tumor angiogenesis.
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Targeting long non-coding RNA-TUG1 inhibits tumor growth and angiogenesis in hepatoblastoma
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Hepatoblastoma | Cell Death Dis | 27362796 |