Hepatitis B；MAPK signaling pathway；ErbB signaling pathway；Cell cycle；PI3K-Akt signaling pathway；Transcriptional misregulation in cancer；Bladder cancer；Wnt signaling pathway；Colorectal cancer；Endometrial cancer；Acute myeloid leukemia；TGF-beta signaling pathway；Hippo signaling pathway；Small cell lung cancer；Proteoglycans in cancer；Thyroid cancer；Jak-STAT signaling pathway；Pathways in cancer；HTLV-I infection；Chronic myeloid leukemia；Epstein-Barr virus infection

Mechanistically, CCR492 functions as a competing endogenous RNA (ceRNA) to antagonize the function of let-7 microRNAs, leading to the de-repression of c-Myc.

The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to regulate c-Myc expression

Hepatitis B；MAPK signaling pathway；ErbB signaling pathway；Cell cycle；PI3K-Akt signaling pathway；Transcriptional misregulation in cancer；Bladder cancer；Wnt signaling pathway；Colorectal cancer；Endometrial cancer；Acute myeloid leukemia；TGF-beta signaling pathway；Hippo signaling pathway；Small cell lung cancer；Proteoglycans in cancer；Thyroid cancer；Jak-STAT signaling pathway；Pathways in cancer；HTLV-I infection；Chronic myeloid leukemia；Epstein-Barr virus infection

Furthermore, CCAT1 could up-regulated c-Myc via its competing endogenous RNA (ceRNA) activity on miR-155.

Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia

Hepatitis B；MAPK signaling pathway；ErbB signaling pathway；Cell cycle；PI3K-Akt signaling pathway；Transcriptional misregulation in cancer；Bladder cancer；Wnt signaling pathway；Colorectal cancer；Endometrial cancer；Acute myeloid leukemia；TGF-beta signaling pathway；Hippo signaling pathway；Small cell lung cancer；Proteoglycans in cancer；Thyroid cancer；Jak-STAT signaling pathway；Pathways in cancer；HTLV-I infection；Chronic myeloid leukemia；Epstein-Barr virus infection

Furthermore, HULC could modulate c-Myc and Bcl-2 by miR-200a as an endogenous sponge.

Long noncoding RNA HULC promotes cell proliferation by regulating PI3K/AKT signaling pathway in chronic myeloid leukemia

Hepatitis B；MAPK signaling pathway；ErbB signaling pathway；Cell cycle；PI3K-Akt signaling pathway；Transcriptional misregulation in cancer；Bladder cancer；Wnt signaling pathway；Colorectal cancer；Endometrial cancer；Acute myeloid leukemia；TGF-beta signaling pathway；Hippo signaling pathway；Small cell lung cancer；Proteoglycans in cancer；Thyroid cancer；Jak-STAT signaling pathway；Pathways in cancer；HTLV-I infection；Chronic myeloid leukemia；Epstein-Barr virus infection

Additionally, we show that the lncRNA-MIF inhibits aerobic glycolysis and tumorigenesis by suppressing c-Myc and miR-586.

LncRNA-MIF, a c-Myc-activated long non-coding RNA, suppresses glycolysis by promoting Fbxw7-mediated c-Myc degradation

Cell cycle；MAPK signaling pathway；Small cell lung cancer；ErbB signaling pathway；PI3K-Akt signaling pathway；Wnt signaling pathway；Chronic myeloid leukemia；TGF-beta signaling pathway；Thyroid cancer；Colorectal cancer； Bladder cancer；Transcriptional misregulation in cancer；Proteoglycans in cancer；Hippo signaling pathway；Jak-STAT signaling pathway；Hepatitis B；Acute myeloid leukemia；Endometrial cancer；HTLV-I infection；Epstein-Barr virus infection；Pathways in cancer

Linc00176 is expressed at a high level only in HCC, and is activated by Myc, Max and AP-4 transcription regulators. Myc also upregulates miR-9 and miR-185. In Linc00176-depleted HCC, these miRNAs were released from Linc00176 and downregulated their target mRNAs. Thus, depletion of Linc00176 disrupted the cell cycle and induced necroptosis in HCC via released tumor suppressor miRNAs

Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs.

Cell cycle；MAPK signaling pathway；Small cell lung cancer；ErbB signaling pathway；PI3K-Akt signaling pathway；Wnt signaling pathway；Chronic myeloid leukemia；TGF-beta signaling pathway；Thyroid cancer；Colorectal cancer； Bladder cancer；Transcriptional misregulation in cancer；Proteoglycans in cancer；Hippo signaling pathway；Jak-STAT signaling pathway；Hepatitis B；Acute myeloid leukemia；Endometrial cancer；HTLV-I infection；Epstein-Barr virus infection；Pathways in cancer

Linc00176 is expressed at a high level only in HCC, and is activated by Myc, Max and AP-4 transcription regulators. Myc also upregulates miR-9 and miR-185. In Linc00176-depleted HCC, these miRNAs were released from Linc00176 and downregulated their target mRNAs. Thus, depletion of Linc00176 disrupted the cell cycle and induced necroptosis in HCC via released tumor suppressor miRNAs

Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs.