LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
PFL let-7d PTAFR PTAFR;PAFR details
Calcium signaling pathway;Neuroactive ligand-receptor interaction;Staphylococcus aureus infection
details
Moreover, PFL competitively sponged the cardio-protective miRNA let-7d in cardiac fibroblasts. Knockdown of platelet activating factor receptor (PTAFR) was shown to affect the pro-fibrotic collagen production mediated by PFL. PTAFR overexpression also led to collagen production and RNA abundance of PTAFR was also regulated by miRNA let-7d.
details
LET's sponge: How the lncRNA PFL promotes cardiac fibrosis.
Cardiac fibrosis Theranostics 29463987