LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
KCNQ1OT1 miR-370 CCNE2 CCNE2;CYCE2 details
Cell cycle; Oocyte meiosis;p53 signaling pathway;PI3K-Akt signaling pathway;Hepatitis B;Measles;Pathways in cancer;Viral carcinogenesis;Prostate cancer;Small cell lung cancer
details
Knockdown of KCNQ1OT1 decreased the expression level of Cyclin E2 (CCNE2) by binding to miR-370. Further, miR-370 bound to CCNE2 3'UTR region and decreased the expression of CCNE2. These results provided a comprehensive analysis of KCNQ1OT1-miR-370-CCNE2 axis in human glioma cells and might provide a novel strategy for glioma treatment.
details
Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells' Malignancy by Activating miR-370/CCNE2 Axis
Glioma Front Cell Neurosci 28381990