mTOR signaling pathway；HIF-1 signaling pathway；Hypertrophic cardiomyopathy (HCM)；Glioma；Prostate cancer；Oocyte meiosis；p53 signaling pathway；PI3K-Akt signaling pathway；Proteoglycans in cancer；Melanoma；Focal adhesion；Long-term depression；Transcriptional misregulation in cancer；Ovarian steroidogenesis；Progesterone-mediated oocyte maturation；Aldosterone-regulated sodium reabsorption；Pathways in cancer；Dilated cardiomyopathy

Furthermore, we identified MHENCR as a competitively endogenous RNA, which specifically bound to miR-425 and miR-489, upregulated their target genes IGF1 and SPIN1 expression, and further activated PI3K-Akt pathway.

Long noncoding RNA MHENCR promotes melanoma progression via regulating miR-425/489-mediated PI3K-Akt pathway

Long-term depression；HIF-1 signaling pathway；Oocyte meiosis；Endocytosis；Prostate cancer；PI3K-Akt signaling pathway；Focal adhesion；Adherens junction；Ovarian steroidogenesis；Progesterone-mediated oocyte maturation；Pathways in cancer；Proteoglycans in cancer；Melanoma； Transcriptional misregulation in cancer；Glioma

The qRT-PCR results also showed that lnc133b negatively regulates miR-133b expression and a Western blot assay showed that lnc133b positively regulates IGF1R expression, indicating that the lnc133b/miR-133b/IGF1R axis is a potential pathway for promoting satellite cell proliferation and repressing their differentiation through the ceRNA mechanism. Building on the findings of previous reports, we constructed the lnc133b/miR-133b/FGFR1 & PP2AC pathway to improve the lnc133b regulation network regulating the proliferation and differentiation of satellite cells.

lnc133b, a novel, long non-coding RNA, regulates bovine skeletal muscle satellite cell proliferation and differentiation by mediating miR-133b.

Adherens junction；HIF-1 signaling pathway；Oocyte meiosis；Endocytosis；PI3K-Akt signaling pathway；Focal adhesion；Prostate cancer；Long-term depression；Ovarian steroidogenesis；Proteoglycans in cancer；Glioma；Progesterone-mediated oocyte maturation；Pathways in cancer；Melanoma；Transcriptional misregulation in cancer

Furthermore, the miR-122-IGF-1R signaling correlated with the dysregulated MALAT1 expression in gastric cancer.

The lncRNA MALAT1 is a novel biomarker for gastric cancer metastasis