LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
HULC | miR-200a-3p | ZEB1 | ZEB1;AREB6;BZP;DELTAEF1;FECD6;NIL2A;PPCD3;TCF8;ZFHEP;ZFHX1A | details
Transcriptional misregulation in cancer
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We conclude that the HULC functioned as a competing endogenous RNA (ceRNA) to mediate EMT via up-regulating ZEB1. In this way, it sequesters the miR-200a-3p signaling pathway to facilitate HCC metastasis.
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LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway
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Hepatocellular Carcinoma | Oncotarget | 27285757 |