LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
H19 | miR-138-5p | SIRT1 | SIRT1;SIR2;SIR2L1;hSIR2 | details
Amphetamine addiction
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Remarkably, SIRT1 was confirmed as a direct target of miR-138-5p in cervical cancer and miR-138-5p exerted the tumor suppressed functions by suppressing SIRT1 expression.
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Decreased Expression of MiR-138-5p by LncRNA H19 in Cervical Cancer Promotes Tumor Proliferation.
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Cervical Cancer | Oncol Res | 28797320 |
ADNCR | miR-204 | SIRT1 | SIRT1;SIR2;SIR2L1;hSIR2 | details
Amphetamine addiction
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Mechanistically, ADNCR inhibited adipocyte differentiation by functioning as a competing endogenous RNA (ceRNA) for miR-204, thereby augmenting the expression of the miR-204 target gene, SIRT1, which is known to inhibit adipocyte differentiation and adipogenic gene expression by docking with NCoR and SMART to repress PPARγ activity
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Long non-coding RNA ADNCR suppresses adipogenic differentiation by targeting miR-204
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Adipogenic | Biochim Biophys Acta | 27156885 |
SIRT1 AS | miR-22 | SIRT1 | SIRT1;SIR2;SIR2L1;Hsir2 | details
Amphetamine addiction
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Our data suggest that SIRT1 AS lncRNA relieves miR-22-induced SIRT1 downregulation by competitively sponging miR-22.
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NAMPT regulates senescence, proliferation, and migration of endothelial progenitor cells through the SIRT1 AS lncRNA/miR-22/SIRT1 pathway
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Cardiovascular Diseases | Biochem Biophys Res Commun | 27569277 |