LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
MALAT1 miR-124 CDK4 CDK4;CMM3;PSK-J3 details
Tight junction;Cell cycle;p53 signaling pathway;Bladder cancer;Non-small cell lung cancer;PI3K-Akt signaling pathway;T cell receptor signaling pathway;Hepatitis B;Melanoma;Glioma;Measles;HTLV-I infection;Pathways in cancer;Small cell lung cancer;Viral carcinogenesis;Pancreatic cancer;Chronic myeloid leukemia
details
Furthermore, MALAT1 acted as an endogenous potent regulator by directly binding to miR-124 and down-regulating miR-124 expression. In addition, MALAT1 reversed the inhibitory effect of miR-124 on breast cancer proliferation and was involved in the cyclin-dependent kinase 4 (CDK4) expression.
details
miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation
Breast Cancer Oncotarget 26918449