Tight junction；Cell cycle；p53 signaling pathway；Bladder cancer；Non-small cell lung cancer；PI3K-Akt signaling pathway；T cell receptor signaling pathway；Hepatitis B；Melanoma；Glioma；Measles；HTLV-I infection；Pathways in cancer；Small cell lung cancer；Viral carcinogenesis；Pancreatic cancer；Chronic myeloid leukemia

Furthermore, MALAT1 acted as an endogenous potent regulator by directly binding to miR-124 and down-regulating miR-124 expression. In addition, MALAT1 reversed the inhibitory effect of miR-124 on breast cancer proliferation and was involved in the cyclin-dependent kinase 4 (CDK4) expression.

miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation