LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
SNHG1 | miR-199a-3p | CDK7 | CDK7;CAK1;CDKN7;HCAK;MO15;STK1;p39MO15 | details
Basal transcription factors;Nucleotide excision repair;Cell cycle
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In addition, miR-199a-3p could target the 3' UTR of CDK7 and suppress CDK7 expression. More importantly, SNHG1 increased CDK7 expression by competitively binding miR-199a-3p, and then promoted cell proliferation and cell cycle progression in prostate cancer.
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SNHG1 lncRNA negatively regulates miR-199a-3p to enhance CDK7 expression and promote cell proliferation in prostate cancer
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Prostate Cancer | Biochem Biophys Res Commun | 28400279 |