LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
CircVMA21 | miR-200c | XIAP | XIAP;API3;BIRC4;IAP-3;ILP1;MIHA;XLP2;hIAP-3;hIAP3 | details
NF-kappa B signaling pathway;Ubiquitin mediated proteolysis;Apoptosis;Focal adhesion;Toxoplasmosis;HTLV-I infection;Pathways in cancer;Small cell lung cancer
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CircVMA21 could alleviate inflammatory cytokines-induced NP cell apoptosis and imbalance between anabolism and catabolism of extracellular matrix through miR-200c-XIAP pathway. It provides a potentially effective therapeutic strategy for IVDD.
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Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein
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Intervertebral disc degeneration | Ann Rheum Dis | 29343508 |