LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
ROR miR-145 FSCN1 FSCN1;FAN1;HSN;SNL;p55 details
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The function of linc-ROR exerted in LAD cells depended on the sponging of miR-145, therefore, releasing the miR-145 target FSCN1, and thus contributing to the acquisition of chemoresistance and EMT phenotypes of docetaxel-resistant LAD cells.
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Long noncoding RNA ROR regulates chemoresistance in docetaxel-resistant lung adenocarcinoma cells via epithelial mesenchymal transition pathway
Lung Adenocarcinoma Oncotarget 28388536
UCA1 miR-145 FSCN1 FSCN1;FAN1;HSN;SNL;p55 details
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Mechanistically, lncRNA-UCA1 induced EMT of bladder cancer cells by upregulating the expression levels of zinc finger E-box binding homeobox 1 and 2 (ZEB1 and ZEB2), and regulated bladder cancer cell migration and invasion by tumor suppressive hsa-miR-145 and its target gene the actin-binding protein fascin homologue 1 (FSCN1).
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Long non-coding RNA urothelial cancer-associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145-ZEB1/2-FSCN3 pathway
Bladder Cancer Cancer Sci 26544536
LincRNA-ROR miR-145 FSCN1 FSCN1;FAN1;HSN;SNL;p55 details
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ROR acted as a competitive endogenous RNA (ceRNA) of miR-145 in ESCC. A novel, effective miR-145 binding site of ROR was discovered. The ROR/miR-145/FSCN1 pathway was shown to take part in the metastasis of ESCC. ROR is likely an oncogene biomarker for ESCC early diagnosis and prognosis
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LincRNA-ROR promotes metastasis and invasion of esophageal squamous cell carcinoma by regulating miR-145/FSCN1
Esophageal squamous cell carcinoma Onco Targets Ther 29430188
XIAP miR-29a-5p FSCN1 FSCN1;FAN1;HSN;SNL;p55 details
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Furthermore, we demonstrated that one miRNA, miR-29a-5p, can bind to both the XIAP and FSCN1 3'UTRs and play an important role in that interactions.
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XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p
Breast Cancer Oncotarget 28186968