LncCeRBase

Welcome to the LncCeRBase DataBase!
LncRNA MiRNA Gene Gene name Pathway Name Description Title Disease/Tissue Journal PubMed ID
circGFRA1 miR-34a GFRA1 GFRA1;GDNFR;GDNFRA;GFR-ALPHA-1;RET1L;RETL1;TRNR1 details
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Via luciferase reporter assays, circGFRA1 and GFRA1 was observed to directly bind to miR-34a. Subsequent experiments showed that circGFRA1 and GFRA1 regulated the expression of each other by sponging miR-34a.
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circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a
Triple negative breast cancer J Exp Clin Cancer Res 29037220
HOTAIR miR-34a Sox2 SOX2;ANOP3;MCOPS3 details
Hippo signaling pathway
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Moreover, full-length HOTAIR transcriptionally inhibits miR-34a specifically, leading to upregulation of Sox2, which is targeted by miR-34a.
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Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells
Breast Cancer PLoS One 28122024