LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
circGFRA1 | miR-34a | GFRA1 | GFRA1;GDNFR;GDNFRA;GFR-ALPHA-1;RET1L;RETL1;TRNR1 | details | details
Via luciferase reporter assays, circGFRA1 and GFRA1 was observed to directly bind to miR-34a. Subsequent experiments showed that circGFRA1 and GFRA1 regulated the expression of each other by sponging miR-34a.
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details
circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a
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Triple negative breast cancer | J Exp Clin Cancer Res | 29037220 |
HOTAIR | miR-34a | Sox2 | SOX2;ANOP3;MCOPS3 | details
Hippo signaling pathway
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details
Moreover, full-length HOTAIR transcriptionally inhibits miR-34a specifically, leading to upregulation of Sox2, which is targeted by miR-34a.
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details
Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells
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Breast Cancer | PLoS One | 28122024 |